Cost guide · prices checked October 2026
How much does semaglutide cost without insurance?
Here is how the cost of semaglutide compares across pharmacies and online care, and what is included in each price.
The short answer
From
$129
/ 4 wks with Leland, all-in
Semaglutide Injection, compounded. Includes provider review, medication and free shipping. No insurance needed, charged only if prescribed.
See if I qualify →Price comparison
What semaglutide costs, compared
Leland
From $129
/ 4 wks, all-in
Medication, licensed provider care and shipping.
Leland's current price
Brand-name pen, self-pay
$349
per 4 pens (4 weeks)
Manufacturer self-pay price at standard doses. New patients pay $199 for the first two fills through Dec 31, 2026. Prescription not included.
Source: NovoCare pricing, October 2026
Brand-name list price
About $1,349
per 4 pens (4 weeks)
Retail list price without insurance or a self-pay program.
Source: manufacturer list price, 2026
What your $129 covers
Pharmacy prices only cover the medication. Leland's price includes everything you need to start and stay on treatment.
Licensed provider review
Usually within 24 hours.
Your medication
Prepared by a licensed U.S. pharmacy.
Free, discreet shipping
To your door in all 50 states.
Ongoing care
Message your care team any time.
Semaglutide cost questions
Compounded medications are prepared by a licensed pharmacy for an individual patient. They are not FDA-approved, and the FDA does not review them for safety, effectiveness or quality. Your provider will explain the options.