Side effects
Hair loss on GLP-1 medication
What the semaglutide and tirzepatide labels record about hair loss, including the rate reported in their placebo arms.
This page is general information, not medical advice. Compounded medications are not FDA-approved and have not been evaluated by the FDA for safety, efficacy, or quality. A qualified clinician determines whether treatment is appropriate for you.
Generated from the family's dataset. No clinician has reviewed this page as a document.
What it is
The documents cited below record this as alopecia, which is the clinical name for hair loss. Searching either word finds the same row in the label.
It is tabulated in the injectable labels and not in the oral one, so this page applies to two of the three medicines this program dispenses.
How often it was reported
The figures below come from the trials the branded products were approved on, and each one is shown against the placebo arm of the same trial. They describe the people in those studies — not anyone on this program, and not the compounded preparations this program dispenses.
The prescribing information for Wegovy lists alopecia among the adverse reactions reported in the trials it was approved on. Measured in 3% of 2,116 adults taking 2.4 mg semaglutide weekly for 68 weeks, against 1% of 1,261 adults on placebo in the same trials. DailyMed, U.S. National Library of Medicine, 2026-06-30
The prescribing information for Zepbound lists alopecia among the adverse reactions reported in the trials it was approved on. Measured in 5% of 941 adults taking 15 mg tirzepatide weekly for 72 weeks, against 1% of 958 adults on placebo in the same trials. DailyMed, U.S. National Library of Medicine, 2026-09-02
What happens on this program
Mention it at the refill check-in. There is nothing about it a support conversation can decide, but the prescribing clinician should know it is happening.
This page has no view on what is causing it in any individual case, and cannot have one.
When to get help
Everything above reports what those documents themselves list. None of it is a judgement about what is happening to you: nobody who wrote this page has seen you, and reading a page is not a consultation.
If something is happening and you are not sure what it means, contact your provider or the pharmacy that dispensed to you. If it is severe, or you think it may be an emergency, call 911 or go to the nearest emergency room.
The prescribing information for Wegovy directs a patient to tell a health care provider about any side effect that bothers them or that does not go away. DailyMed, U.S. National Library of Medicine, 2026-06-30